Monitoring Lipophilic Toxins in Seawater Using Dispersive Liquid-Liquid Microextraction and Liquid Chromatography with Triple Quadrupole Mass Spectrometry

The use of dispersive liquid-liquid microextraction (DLLME) is proposed for the preconcentration of thirteen lipophilic marine toxins in seawater samples. For this purpose, 0.5 mL of methanol and 440 mu L of chloroform were injected into 12 mL of sample. The enriched organic phase, once evaporated and reconstituted in methanol, was analyzed by reversed-phase liquid chromatography with triple-quadrupole tandem mass spectrometry. A central composite design multivariate method was used to optimize the interrelated parameters affecting DLLME efficiency. The absence of any matrix effect in the samples allowed them to be quantified against aqueous standards. The optimized procedure was validated by recovery studies, which provided values in the 82-123% range. The detection limits varied between 0.2 and 5.7 ng L-1, depending on the analyte, and the intraday precision values were in the 0.1-7.5% range in terms of relative standard deviation. Ten water samples taken from different points of the Mar Menor lagoon were analyzed and were found to be free of the studied toxins.

Datos y Recursos

Cite como

Oller-Ruiz A. Campillo N. Hernandez-Cordoba M. Gilabert J. y Vinas P. Monitoring Lipophilic Toxins in Seawater Using Dispersive Liquid-Liquid Microextraction and Liquid Chromatography with Triple Quadrupole Mass Spectrometry. MDPI, 2021. https://doi.org/10.3390/toxins13010057

Clipboard Icon
Recuperado: 08 Nov 2025 03:49:25
RIS BibTeX

Metadatos
Descargar
DCAT-AP/NTI-RISP

Información básica
Tipo de recurso Artículo
Fecha de creación 05-11-2024
Fecha de última modificación 05-11-2024
Mostrar histórico de cambios
Identificador de los metadatos dd7326be-c55f-577e-b5ca-f55df15d299b
Idioma de los metadatos Español
Temáticas (NTI-RISP)
Categoría del conjunto de alto valor (HVD) Observación de la Tierra y medio ambiente
Categoría temática ISO 19115 biota
URI de palabras clave
Información bibliográfica
Nombre del autor Oller-Ruiz, A., Campillo, N., Hernandez-Cordoba, M., Gilabert, J. y Vinas, P.
Nombre del editor MDPI
Identificador alternativo DOI: 10.3390/toxins13010057
Identificador del autor
Email del autor ainhoa.oller@um.es
Web del autor
Procedencia
Declaración de linaje
Perfil de Metadatos
Notas sobre la versión
Versión